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Introduction to Active Ingredients

Pomegranate extract

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Update time : 2020-04-23 16:23:28
The active substance extracted from pomegranate peel, seeds and juice contain polyphenols, flavonoids, alkaloids, organic acids, and estrogen-like ingredients. It has a variety of pharmacological functions, such as antioxidants, scavenging free radicals, preventing cardiovascular and cerebrovascular diseases and improving female menopausal syndrome.
In addition to steroids, phospholipids, triglycerides, volatile oils, amino acids and minerals, the main chemical components are polyphenols, flavonoids, alkaloids, and organic acids.
1. Extract polyphenolic compounds from pomegranate peel and separate and obtain pomegranate, pomegranate forest, casuarina, pomegranate skin A, pomegranate skin B, tannin, ellagic acid, gallic acid and British ellagic acid, etc Gallic acid, quercetin, chlorogenic acid, phlorizin, caffeic acid, protocatechuic acid, catechins, coumaric acid, etc. are extracted from pomegranate juice, among which gallic acid and catechins are higher.
2. Flavonoids in pomegranate skin include geranium, delphinium, and rutin. Pomegranate peel also contains three flavonol phytoestrogens, digitalis, quercetin, and cocoa phenol. Pomegranate seeds also contain two isoflavone phytoestrogens, namely 5,7,4'-trihydroxy isoflavone and 7, 4'-dihydroxy isoflavone.
3. The alkaloid compound pomegranate mainly contains piperidine and pyrrolidine alkaloids. Piperidine alkaloids include garnet, N-methyl garnet, pseudo-garnet, N-acetyl garnet and the like. The types of piperidine-type Chemicalbook alkaloids contained in different parts of pomegranate are different. N-acetyl garnet, 2- (2-hydroxypropyl) -in 2-piperidine, Serdidine and N-acetyl Sedridine isomers are distributed in almost all parts of the garnet. Pomegranate skin, pseudo-pomegranate skin, N-methyl pomegranate skin, and is garnet skin are mainly found in root bark, stem bark, branch bark, and peel. 2- (2-Hydroxypropyl) -Yin 1-piperidine, 2- (2-propenyl) -Yin 1-piperidine and nor garnet are higher in the root bark. The pyrrolidine alkaloids in pomegranate are mainly coumarin and norcodeine, both of which are mainly present in the root bark, but the content is not high.
4. Organic acid compound Pomegranate seeds are rich in unsaturated fatty acid compounds. The juice is mainly composed of multi-component linear carboxylic acid, with the highest citric acid content, the average content can reach 4.85g · L-1, followed by L -malic acid (average content is 1.75g ​​· L-1), and tartaric acid and oxalic acid, Quinic acid and succinic acid.
5. Other ingredients, steroids, phospholipids, triglycerides, and volatile oil are all distributed in pomegranate seeds, while amino acids and minerals are distributed in pomegranate juice.
 
1. Anti-ultraviolet radiation research shows that pomegranate juice, pomegranate extract and pomegranate oil all have anti-ultraviolet effects and become useful auxiliary ingredients in cosmetics.
2. Clinical trials and animal experiments to improve metabolic syndrome show that pomegranate juice, pomegranate extract, and pomegranate flower extract have significant anti-atherosclerosis, anti-hypertensive and anti-inflammatory activities and can be used to treat metabolic syndrome.
3. Antibacterial activity Antibacterial, antiviral activity Tannic acid in pomegranate extract is its antiviral active ingredient. The ellagic acid, gallic acid, pomegranate tannin and pomegranate contained in the pomegranate extract have significant inhibitory effects on Staphylococcus aureus, Escherichia coli, Candida, Pseudomonas and Cryptococcus in vitro. The minimum inhibitory concentrations of guava against Candida albicans and Candida byproducts were 3.9 and 1.9 g · mL-1, respectively, and showed good synergistic antibacterial effects with fluconazole. The antiviral active ingredient in polyphenol extract. The IC50 of the parasite-resistant immature pomegranate peel extract chloroquine-sensitive D10 Plasmodium and chloroquine-resistant W2 Plasmodium chemistry books were 4.5 g and 2.8 g · mL-1, respectively. Pomegranate extract shows good anti-trichomoniasis activity in vitro.
4. Antioxidant activity The antioxidant content in pomegranate is 11 times that of lemon, 39 times that of apple and 283 times that of watermelon. The main antioxidant in pomegranate is an ellagitannin, which is metabolized by microbes in the intestine into urolithin and enters the blood circulation, while urolithin A, C, D, etc. all show strong antioxidant activity, And the activity is significantly higher than ellagic acid and punicalagin. The activity in animals is mainly manifested in the following aspects: stasis has a protective effect on gastric mucosal damage caused by the toxic effect of alcohol or aspirin in chemistry rats; stasis has a protective effect on the toxic effect of alcohol or aspirin. Protects hypoxic brain damage in young rats; weaknesses; Ulmus eliminates liver toxicity caused by iron and nitrogen.
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