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Pomegranate Extract Uses

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Update time : 2019-12-25 17:37:07
Pomegranate extract is an active substance extracted from pomegranate's peel, seeds, and juice. It contains polyphenols, flavonoids, alkaloids, organic acids, and estrogen-like ingredients. It has various pharmacological functions such as anti-oxidation, scavenging free radicals, preventing cardiovascular and cerebrovascular diseases, and improving women's menopause syndrome.
The main chemical components are polyphenols, flavonoids, alkaloids and organic acids. In addition, they also contain steroids, phospholipids, triglycerides, volatile oils, amino acids and minerals.
1. Polyphenols are extracted from pomegranate peel to obtain pomeloside, pomegranate forest, casuarina, pomegranate pitting A, pomegranate pitting B, tannin, ellagic acid, gallic acid and English oak tannin Acid, etc .; gallic acid, quercetin, chlorogenic acid, phlorizin, caffeic acid, catechin, catechin and coumarin, etc. are extracted and separated from pomegranate juice, among which gallic acid and catechin content Higher.
2. Flavonoids Flavonoids in pomegranate peel include pelargoniums, delphiniums, rutins, and the like. Pomegranate peel also contains 3 kinds of flavonol phytoestrogens, namely foxglove flavonoids, quercetin and phenanthrene. Pomegranate seeds also contain two isoflavone phytoestrogens, namely 5,7,4′-trihydroxy isoflavones and 7,4′-dihydroxy isoflavones.
3. Alkaloid compounds Pomegranate contains piperidine and pyrrolidine alkaloids. Piperidine alkaloids include pomegranate, N-methyl pomegranate, pseudo- pomegranate, N-acetyl pomegranate, and the like. The types of piperidine Chemicalbook alkaloids contained in different parts of pomegranate are different, two are N-acetyl pomegranate, 2- (2, -hydroxypropyl) -yin 1-piperidine, sedridine, and N-acetyl sedridine Isomers are distributed in almost all parts of the pomegranate. The pomegranate, pseudo papaverine, N-methyl papaverine, and iso pomegranate are mainly found in root bark, stem bark, branch bark, and peel. The content of 2- (2, -hydroxypropyl) -an-piperidine, 2- (2, -propenyl) -an-piperidine and norophylline is higher in the root bark. Pyrrolidine alkaloids in pomegranate are mainly cumine and norcolline, both of which are mainly present in the root bark, but their content is not high.
4. Organic acid compounds Pomegranate seeds are rich in unsaturated fatty acid compounds. The fruit juice is dominated by multiple linear carboxylic acids, among which the citric acid content is the highest, with an average content of 4.85g · L-1, followed by L-malic acid (average content 1.75g ​​· L-1), tartaric acid, and oxalic acid , (—)-Quinic acid and succinic acid. 5. Other steroids, phospholipids, triglycerides, and volatile oils are distributed in pomegranate seeds, and amino acids and minerals are distributed in pomegranate juice.

1. Anti-ultraviolet radiation research shows that pomegranate juice, pomegranate extract and pomegranate oil all have the effect of resisting ultraviolet damage and is expected to become a useful auxiliary ingredient in cosmetics.
2. Clinical trials and animal experiments to improve metabolic syndrome show that pomegranate juice, pomegranate extract, and pomegranate flower extract have significant anti-atherosclerotic, anti-hypertensive, and anti-inflammatory activities and are expected to be used in the treatment of metabolic syndrome .
3. Antimicrobial activity Antibacterial and antiviral activity Tannin in pomegranate extract is its antiviral active component. Ellagic acid, gallic acid, pomegranate tannin and pomegranate contained in pomegranate extract have significant inhibitory effects on Staphylococcus aureus, E. coli, Candida, Pseudomonas, Cryptococcus Bacterial effect. The lowest bacteriostatic concentration of punicin on Candida albicans and Candida subtilis is 3.9 and 1.9 μg · mL-1, respectively, and it shows good synergistic antibacterial effect with fluconazole. Antiviral active ingredient in polyphenol extract. The IC50 of the parasite-resistant immature pomegranate peel extracts, D10 Plasmodium sensitive to chloroquine and W2 Plasmodium resistant to chloroquine, were 4.5 and 2.8 g · mL-1, respectively. The pomegranate extract showed good anti-trichomoniasis activity in vitro.
4. Antioxidant activity Pomegranate has 11 times the antioxidant content of lemon, 39 times of apple, and 283 times of watermelon. The main antioxidants in pomegranate are tannins, which are metabolized into urolithin by the microorganisms in the intestinal tract and enter the blood circulation, while urolithin A, C, and D all show strong Antioxidant activity, and the activity was significantly higher than ellagic acid and punicoside. The animal's in vivo activity is mainly manifested in the following aspects: Stasis has a protective effect on gastric mucosal damage in rats caused by the toxic effects of alcohol or aspirin; it has a protective effect on hypoxic damage to the brain of young rats; pelvis prevents male rabbits from erectile weakness ; Ulmus eliminates liver toxicity caused by ferric nitrogen triacetate [Fe-NTA]. Clinically, it is often seen that the indicators reflecting liver function have improved significantly, to avoid the occurrence of balloon-like degeneration of the liver, steatosis of the liver, and hepatic necrosis; in the cardiovascular system Pomegranate juice can reduce the content of LDL and total cholesterol in the blood, and has the effect of lowering blood pressure and reducing the occurrence of carotid arteriosclerosis.
5. Effect on bone and joints Pomegranate extract can inhibit the proteoglycan degradation induced by interleukin-1 in cartilage explants. This shows that pomegranate extract can inhibit cartilage degradation in osteoarthritis, and is therefore expected to be a nutritional supplement to maintain joint integrity and function.
6. Effects on neonatal hypoxia and ischemic brain damage. Experiments on pregnant mice found that compared with placebo-pregnant rats, pregnant rats who took pomegranate juice suffered from experimental induction. The chance of brain damage was significantly reduced by 64%, and the activity of caspase in the hippocampus was significantly reduced by 84%. This shows that the antioxidant properties of pomegranate juice can play a neuroprotective role, and that this effect can affect the fetus through the mother.